Yuxian Liu and Wei Yao

Sugarcane genome

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  • Nat Genet | Article |

    Whole-genome sequencing of 175 Mongolians representing six tribes highlights population-specific genetic architecture and substantial gene flow among northern Eurasian populations, including derived alleles shared by Mongolians and Finns.

    • Haihua Bai
    • , Xiaosen Guo
    • , Narisu Narisu
    • , Tianming Lan
    • , Qizhu Wu
    • , Yanping Xing
    • , Yong Zhang
    • , Stephen R. Bond
    • , Zhili Pei
    • , Yanru Zhang
    • , Dandan Zhang
    • , Jirimutu Jirimutu
    • , Dong Zhang
    • , Xukui Yang
    • , Morigenbatu Morigenbatu
    • , Li Zhang
    • , Bingyi Ding
    • , Baozhu Guan
    • , Junwei Cao
    • , Haorong Lu
    • , Yiyi Liu
    • , Wangsheng Li
    • , Ningxin Dang
    • , Mingyang Jiang
    • , Shenyuan Wang
    • , Huixin Xu
    • , Dingzhu Wang
    • , Chunxia Liu
    • , Xin Luo
    • , Ying Gao
    • , Xueqiong Li
    • , Zongze Wu
    • , Liqing Yang
    • , Fanhua Meng
    • , Xiaolian Ning
    • , Hashenqimuge Hashenqimuge
    • , Kaifeng Wu
    • , Bo Wang
    • , Suyalatu Suyalatu
    • , Yingchun Liu
    • , Chen Ye
    • , Huiguang Wu
    • , Kalle Leppälä
    • , Lu Li
    • , Lin Fang
    • , Yujie Chen
    • , Wenhao Xu
    • , Tao Li
    • , Xin Liu
    • , Xun Xu
    • , Christopher R. Gignoux
    • , Huanming Yang
    • , Lawrence C. Brody
    • , Jun Wang
    • , Karsten Kristiansen
    • , Burenbatu Burenbatu
    • , Huanmin Zhou
    •  & Ye Yin

  • Nat Genet | Letter |

    Analysis of 1,007 sibling pairs from 251 families identifies 878 de novo mutations shared by siblings at 448 sites. Recurrence probability based on parental somatic mosaicism, sibling sharing, parent of origin, mutation type and genomic position can range from 0.011% to 28.5%.

    • Hákon Jónsson
    • , Patrick Sulem
    • , Gudny A. Arnadottir
    • , Gunnar Pálsson
    • , Hannes P. Eggertsson
    • , Snaedis Kristmundsdottir
    • , Florian Zink
    • , Birte Kehr
    • , Kristjan E. Hjorleifsson
    • , Brynjar Ö. Jensson
    • , Ingileif Jonsdottir
    • , Sigurdur Einar Marelsson
    • , Sigurjon Axel Gudjonsson
    • , Arnaldur Gylfason
    • , Adalbjorg Jonasdottir
    • , Aslaug Jonasdottir
    • , Simon N. Stacey
    • , Olafur Th. Magnusson
    • , Unnur Thorsteinsdottir
    • , Gisli Masson
    • , Augustine Kong
    • , Bjarni V. Halldorsson
    • , Agnar Helgason
    • , Daniel F. Gudbjartsson
    •  & Kari Stefansson

  • Nat Genet | Article |

    Eight genome-wide CRISPR screens identify genes required for substrate-specific phagocytosis. The study highlights roles for NHLRC2 in filopodia formation, very-long-chain fatty acids in substrate-specific phagocytosis and TM2D3 in uptake of amyloid-β aggregates.

    • Michael S. Haney
    • , Christopher J. Bohlen
    • , David W. Morgens
    • , James A. Ousey
    • , Amira A. Barkal
    • , C. Kimberly Tsui
    • , Braeden K. Ego
    • , Roni Levin
    • , Roarke A. Kamber
    • , Hannah Collins
    • , Andrew Tucker
    • , Amy Li
    • , Daan Vorselen
    • , Lorenzo Labitigan
    • , Emily Crane
    • , Evan Boyle
    • , Lihua Jiang
    • , Joanne Chan
    • , Esther Rincón
    • , William J. Greenleaf
    • , Billy Li
    • , Michael P. Snyder
    • , Irving L. Weissman
    • , Julie A. Theriot
    • , Sean R. Collins
    • , Ben A. Barres
    •  & Michael C. Bassik

  • Nat Genet | Article |

    Analysis of genotyping-by-sequencing data for more than 20,000 barley accessions from a German genebank provides a framework for genomics-assisted genebank management and analysis of large germplasm collections for important crops.

    • Sara G. Milner
    • , Matthias Jost
    • , Shin Taketa
    • , Elena Rey Mazón
    • , Axel Himmelbach
    • , Markus Oppermann
    • , Stephan Weise
    • , Helmut Knüpffer
    • , Martín Basterrechea
    • , Patrick König
    • , Danuta Schüler
    • , Rajiv Sharma
    • , Raj K. Pasam
    • , Twan Rutten
    • , Ganggang Guo
    • , Dongdong Xu
    • , Jing Zhang
    • , Gerhard Herren
    • , Thomas Müller
    • , Simon G. Krattinger
    • , Beat Keller
    • , Yong Jiang
    • , Maria Y. González
    • , Yusheng Zhao
    • , Antje Habekuß
    • , Sandra Färber
    • , Frank Ordon
    • , Matthias Lange
    • , Andreas Börner
    • , Andreas Graner
    • , Jochen C. Reif
    • , Uwe Scholz
    • , Martin Mascher
    •  & Nils Stein

Current Issue |

Volume 50 Issue 12

Latest Research

  • Nat Genet | Letter |

    Analysis of mutational asymmetry with respect to the direction of replication and transcription suggests that error-prone damage bypass on the lagging strand has a major role in human germline and cancer mutations.

    • Vladimir B. Seplyarskiy
    • , Evgeny E. Akkuratov
    • , Natalia Akkuratova
    • , Maria A. Andrianova
    • , Sergey I. Nikolaev
    • , Georgii A. Bazykin
    • , Igor Adameyko
    •  & Shamil R. Sunyaev

  • Nat Genet | Brief Communication |

    The long noncoding RNA SCHLAP1 has been reported to act by depleting the SWI/SNF complex from genomic sites, but new data show that SWI/SNF remains localized to chromatin in the presence of SCHLAP1, suggesting that SCHLAP1 may act independently of SWI/SNF.

    • Jesse R. Raab
    • , Keriayn N. Smith
    • , Camarie C. Spear
    • , Carl J. Manner
    • , J. Mauro Calabrese
    •  & Terry Magnuson

  • Nat Genet | Analysis |

    Including patient-specific information about nearby somatic and germline alterations improves the accuracy of neoantigen prediction, potentially impacting cancer vaccine design.

    • Jasreet Hundal
    • , Susanna Kiwala
    • , Yang-Yang Feng
    • , Connor J. Liu
    • , Ramaswamy Govindan
    • , William C. Chapman
    • , Ravindra Uppaluri
    • , S. Joshua Swamidass
    • , Obi L. Griffith
    • , Elaine R. Mardis
    •  & Malachi Griffith

  • Nat Genet | Letter | | open

    The improved genome assemblies of allotetraploid cotton species Gossypium hirsutum and Gossypium barbadense provide insights into cotton evolution and inform the construction of introgression lines used to identify loci associated with fiber quality.

    • Maojun Wang
    • , Lili Tu
    • , Daojun Yuan
    • , De Zhu
    • , Chao Shen
    • , Jianying Li
    • , Fuyan Liu
    • , Liuling Pei
    • , Pengcheng Wang
    • , Guannan Zhao
    • , Zhengxiu Ye
    • , Hui Huang
    • , Feilin Yan
    • , Yizan Ma
    • , Lin Zhang
    • , Min Liu
    • , Jiaqi You
    • , Yicheng Yang
    • , Zhenping Liu
    • , Fan Huang
    • , Baoqi Li
    • , Ping Qiu
    • , Qinghua Zhang
    • , Longfu Zhu
    • , Shuangxia Jin
    • , Xiyan Yang
    • , Ling Min
    • , Guoliang Li
    • , Ling-Ling Chen
    • , Hongkun Zheng
    • , Keith Lindsey
    • , Zhongxu Lin
    • , Joshua A. Udall
    •  & Xianlong Zhang

  • Nat Genet | Article |

    Genome-wide association analyses based on whole-genome sequencing and imputation identify 40 new risk variants for colorectal cancer, including a strongly protective low-frequency variant at CHD1 and loci implicating signaling and immune function in disease etiology.

    • Jeroen R. Huyghe
    • , Stephanie A. Bien
    • , Tabitha A. Harrison
    • , Hyun Min Kang
    • , Sai Chen
    • , Stephanie L. Schmit
    • , David V. Conti
    • , Conghui Qu
    • , Jihyoun Jeon
    • , Christopher K. Edlund
    • , Peyton Greenside
    • , Michael Wainberg
    • , Fredrick R. Schumacher
    • , Joshua D. Smith
    • , David M. Levine
    • , Sarah C. Nelson
    • , Nasa A. Sinnott-Armstrong
    • , Demetrius Albanes
    • , M. Henar Alonso
    • , Kristin Anderson
    • , Coral Arnau-Collell
    • , Volker Arndt
    • , Christina Bamia
    • , Barbara L. Banbury
    • , John A. Baron
    • , Sonja I. Berndt
    • , Stéphane Bézieau
    • , D. Timothy Bishop
    • , Juergen Boehm
    • , Heiner Boeing
    • , Hermann Brenner
    • , Stefanie Brezina
    • , Stephan Buch
    • , Daniel D. Buchanan
    • , Andrea Burnett-Hartman
    • , Katja Butterbach
    • , Bette J. Caan
    • , Peter T. Campbell
    • , Christopher S. Carlson
    • , Sergi Castellví-Bel
    • , Andrew T. Chan
    • , Jenny Chang-Claude
    • , Stephen J. Chanock
    • , Maria-Dolores Chirlaque
    • , Sang Hee Cho
    • , Charles M. Connolly
    • , Amanda J. Cross
    • , Katarina Cuk
    • , Keith R. Curtis
    • , Albert de la Chapelle
    • , Kimberly F. Doheny
    • , David Duggan
    • , Douglas F. Easton
    • , Sjoerd G. Elias
    • , Faye Elliott
    • , Dallas R. English
    • , Edith J. M. Feskens
    • , Jane C. Figueiredo
    • , Rocky Fischer
    • , Liesel M. FitzGerald
    • , David Forman
    • , Manish Gala
    • , Steven Gallinger
    • , W. James Gauderman
    • , Graham G. Giles
    • , Elizabeth Gillanders
    • , Jian Gong
    • , Phyllis J. Goodman
    • , William M. Grady
    • , John S. Grove
    • , Andrea Gsur
    • , Marc J. Gunter
    • , Robert W. Haile
    • , Jochen Hampe
    • , Heather Hampel
    • , Sophia Harlid
    • , Richard B. Hayes
    • , Philipp Hofer
    • , Michael Hoffmeister
    • , John L. Hopper
    • , Wan-Ling Hsu
    • , Wen-Yi Huang
    • , Thomas J. Hudson
    • , David J. Hunter
    • , Gemma Ibañez-Sanz
    • , Gregory E. Idos
    • , Roxann Ingersoll
    • , Rebecca D. Jackson
    • , Eric J. Jacobs
    • , Mark A. Jenkins
    • , Amit D. Joshi
    • , Corinne E. Joshu
    • , Temitope O. Keku
    • , Timothy J. Key
    • , Hyeong Rok Kim
    • , Emiko Kobayashi
    • , Laurence N. Kolonel
    • , Charles Kooperberg
    • , Tilman Kühn
    • , Sébastien Küry
    • , Sun-Seog Kweon
    • , Susanna C. Larsson
    • , Cecelia A. Laurie
    • , Loic Le Marchand
    • , Suzanne M. Leal
    • , Soo Chin Lee
    • , Flavio Lejbkowicz
    • , Mathieu Lemire
    • , Christopher I. Li
    • , Li Li
    • , Wolfgang Lieb
    • , Yi Lin
    • , Annika Lindblom
    • , Noralane M. Lindor
    • , Hua Ling
    • , Tin L. Louie
    • , Satu Männistö
    • , Sanford D. Markowitz
    • , Vicente Martín
    • , Giovanna Masala
    • , Caroline E. McNeil
    • , Marilena Melas
    • , Roger L. Milne
    • , Lorena Moreno
    • , Neil Murphy
    • , Robin Myte
    • , Alessio Naccarati
    • , Polly A. Newcomb
    • , Kenneth Offit
    • , Shuji Ogino
    • , N. Charlotte Onland-Moret
    • , Barbara Pardini
    • , Patrick S. Parfrey
    • , Rachel Pearlman
    • , Vittorio Perduca
    • , Paul D. P. Pharoah
    • , Mila Pinchev
    • , Elizabeth A. Platz
    • , Ross L. Prentice
    • , Elizabeth Pugh
    • , Leon Raskin
    • , Gad Rennert
    • , Hedy S. Rennert
    • , Elio Riboli
    • , Miguel Rodríguez-Barranco
    • , Jane Romm
    • , Lori C. Sakoda
    • , Clemens Schafmayer
    • , Robert E. Schoen
    • , Daniela Seminara
    • , Mitul Shah
    • , Tameka Shelford
    • , Min-Ho Shin
    • , Katerina Shulman
    • , Sabina Sieri
    • , Martha L. Slattery
    • , Melissa C. Southey
    • , Zsofia K. Stadler
    • , Christa Stegmaier
    • , Yu-Ru Su
    • , Catherine M. Tangen
    • , Stephen N. Thibodeau
    • , Duncan C. Thomas
    • , Sushma S. Thomas
    • , Amanda E. Toland
    • , Antonia Trichopoulou
    • , Cornelia M. Ulrich
    • , David J. Van Den Berg
    • , Franzel J. B. van Duijnhoven
    • , Bethany Van Guelpen
    • , Henk van Kranen
    • , Joseph Vijai
    • , Kala Visvanathan
    • , Pavel Vodicka
    • , Ludmila Vodickova
    • , Veronika Vymetalkova
    • , Korbinian Weigl
    • , Stephanie J. Weinstein
    • , Emily White
    • , Aung Ko Win
    • , C. Roland Wolf
    • , Alicja Wolk
    • , Michael O. Woods
    • , Anna H. Wu
    • , Syed H. Zaidi
    • , Brent W. Zanke
    • , Qing Zhang
    • , Wei Zheng
    • , Peter C. Scacheri
    • , John D. Potter
    • , Michael C. Bassik
    • , Anshul Kundaje
    • , Graham Casey
    • , Victor Moreno
    • , Goncalo R. Abecasis
    • , Deborah A. Nickerson
    • , Stephen B. Gruber
    • , Li Hsu
    •  & Ulrike Peters
More Latest Research More Latest Research

News & Comment

  • Nat Genet | Correspondence |

    • Weiyin Zhou
    • , Mitchell J. Machiela
    • , Neal D. Freedman
    • , Nathaniel Rothman
    • , Nuria Malats
    • , Casey Dagnall
    • , Neil Caporaso
    • , Lauren T. Teras
    • , Mia M. Gaudet
    • , Susan M. Gapstur
    • , Victoria L. Stevens
    • , Kevin B. Jacobs
    • , Joshua Sampson
    • , Demetrius Albanes
    • , Stephanie Weinstein
    • , Jarmo Virtamo
    • , Sonja Berndt
    • , Robert N. Hoover
    • , Amanda Black
    • , Debra Silverman
    • , Jonine Figueroa
    • , Montserrat Garcia-Closas
    • , Francisco X. Real
    • , Julie Earl
    • , Gaelle Marenne
    • , Benjamin Rodriguez-Santiago
    • , Margaret Karagas
    • , Alison Johnson
    • , Molly Schwenn
    • , Xifeng Wu
    • , Jian Gu
    • , Yuanqing Ye
    • , Amy Hutchinson
    • , Margaret Tucker
    • , Luis A. Perez-Jurado
    • , Michael Dean
    • , Meredith Yeager
    •  & Stephen J. Chanock

  • Nat Genet | News & Views |

    The genomes for essentially all worm parasites of humans are in hand thanks to a new study. Now we have to use them.

    • Paul W. Sternberg

  • Nat Genet | Editorial |

    Well-designed science education via social media may help to reach a larger group of audiences with the aim of reducing the boundaries between researchers and the public. This may, in turn, move basic science toward translational improvement in human health and agriculture.

More News & Comment More News & Comment

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